What is your liver? Let’s get to know this friendly fella that lives on the right upper quadrant of your abdomen. Your liver is your friend and is incredibly vital to your overall health. You may have heard that the liver can regenerate itself, but it is not magical. Years of abuse to your liver can impair its ability to heal itself. Damage to your liver can happen through over the counter medications, prescription medications, a poor diet or obesity, hepatitis infections, uncontrolled diabetes, and of course alcohol misuse.